Article
Interleukin-1 cluster gene polymorphisms in childhood IgA nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2009
Hahn Won Ho, Cho Byoung Soo, Kim Sung Do, Kim Su Kang, Kang Sungwook
Abstract excerpt
We have carried out a study with the aim of investigating the association between single nucleotide polymorphisms (SNPs) of the IL-1 gene cluster and childhood IgA nephropathy (IgAN). SNPs of the IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist (RN) genes (IL1A, IL1B, and IL1RN, respectively) were analyzed in 182 patients with childhood IgAN and in 500 healthy controls. The IgAN patients were also dichotomized...
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