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Article

Performance characteristics of Allele-Specific PCR (ASPCR) in detecting drug resistance mutations among non-B HIV-1 Variants.

Journal of virological methods - 1 Jan 2024

Adawaye Chatté, Fokam Joseph, Kamangu Erick Ntambwe, Ngwese Derrick Tambe Ayuk, Susin Fabrice, Moussa Ali Mahamat, Hig-Zounet BertinTchombou, Mad-Toingué Joseph, Tidjani Abdelsalam, Vaira Dolores, Moutschen Michel

Abstract excerpt

Allele-Specific Polymerase Chain Reaction (ASPCR) is an affordable point-mutation assay whose validation could improve the detection of HIV-1 drug resistance mutations (DRMs) in resource-limited settings (RLS). We assessed the performance of ASPCR onforty-four non-B HIV-1 plasma samples from patients who were ARV treated in failure in N'Djamena-Chad. Viral RNA was reverse-transcribed and amplified using...

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Identifiers

PMID: 38000668
DOI: 10.1016/j.jviromet.2023.114856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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