Article
Recent insights regarding the molecular basis of myeloproliferative neoplasms.
The Korean journal of internal medicine - 1 Jan 2020
Jang Mi-Ae, Choi Chul Won
Abstract excerpt
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of clonal disorders characterized by the overproduction of mature blood cells that have an increased risk of thrombosis and progression to acute myeloid leukemia. Next-generation sequencing studies have provided key insights regarding the molecular mechanisms of MPNs. MPN driver mutations in genes associated with the JAK-STAT pathway include JAK2...
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