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Phenotype and oxidative burst of low-density neutrophil subpopulations are altered in common variable immunodeficiency patients.

Cytometry. Part B, Clinical cytometry - 1 Mar 2024

Slanina Peter, Stichova Julie, Bosakova Veronika, Zambo Iva Staniczkova, Kohoutkova Marcela Hortova, Laznickova Petra, Chovancova Zita, Litzman Jiri, Plucarova Terezie, Fric Jan, Vlkova Marcela

Abstract excerpt

Common variable immunodeficiency disorder (CVID) is the most common form of primary antibody immunodeficiency. Due to low antibody levels, CVID patients receive intravenous or subcutaneous immunoglobulin replacement therapy as treatment. CVID is associated with the chronic activation of granulocytes, including an increased percentage of low-density neutrophils (LDNs). In this study, we examined changes in the...

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PMID: 37997558
DOI: 10.1002/cyto.b.22150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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