Article
FKBP3 aggravates the malignant phenotype of diffuse large B-cell lymphoma by PARK7-mediated activation of Wnt/β-catenin signalling.
Journal of cellular and molecular medicine - 1 Jan 2024
Xing Xiaojing, Liu Meichen, Wang Xuguang, Guo Qianxue, Wang Hongyue, Wang Wenxue
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is difficult to treat due to the high recurrence rate and therapy intolerance, so finding potential therapeutic targets for DLBCL is critical. FK506-binding protein 3 (FKBP3) contributes to the progression of various cancers and is highly expressed in DLBCL, but the role of FKBP3 in DLBCL and its mechanism are not clear. Our study demonstrated that FKBP3 aggravated the...
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