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Sex‐specific genetic architecture of late‐life memory performance

20 Nov 2023

Abstract excerpt

BACKGROUND: Women demonstrate a memory advantage when cognitively healthy yet lose this advantage to men in Alzheimer's disease. However, the genetic underpinnings of this sex difference in memory performance remain unclear. METHODS: = 15,641). Leveraging harmonized memory composite scores from four cohorts of cognitive aging and AD, we performed sex-stratified and sex-interaction genome-wide association studies...

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PMID: 37984853
DOI: 10.1002/alz.13507

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