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Article

APOE ε4-Allele in Middle-Aged and Older Autistic Adults: Associations with Verbal Learning and Memory.

International journal of molecular sciences - 5 Nov 2023

Harker Samantha A, Al-Hassan Lamees, Huentelman Matthew J, Braden B Blair, Lewis Candace R

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disability and recent evidence suggests that autistic adults are more likely to develop Alzheimer's disease (Alz) and other dementias compared to neurotypical (NT) adults. The ε4-allele of the Apolipoprotein E (APOE) gene is the strongest genetic risk factor for Alz and negatively impacts cognition in middle-aged and older (MA+) adults. This study aimed to...

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Identifiers

PMID: 37958971
DOI: 10.3390/ijms242115988
PMCID: PMC10650864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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