Article
No association between the APOE gene and autism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Feb 2004
Raiford K L, Shao Y, Allen I C, Martin E R, Menold M M, Wright H H, Abramson R K, Worley G, DeLong G R, Vance J M, Cuccaro M L, Gilbert J R, Pericak-Vance M A
Abstract excerpt
Autism is a neurodevelopmental disorder characterized by stereotypic and repetitive behavior and interests, together with social and communicative deficiencies. The results of several genomic screens suggest the presence of an autism susceptibility locus on chromosome 19p13.2-q13.4. The apolipoprotein E (APOE) gene on chromosome 19 encodes for a protein, apoE, whose different isoforms (E2, E3, E4) influence...
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