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Article

Mutational antigenic landscape of prevailing H9N2 influenza virus hemagglutinin spectrum.

Cell reports - 28 Nov 2023

Zhang Jiahao, Wang Xiaomin, Chen Yiqun, Ye Hejia, Ding Shiping, Zhang Tao, Liu Yi, Li Huanan, Huang Lihong, Qi Wenbao, Liao Ming

Abstract excerpt

H9N2 influenza viruses are globally endemic in birds, and a sharp increase in human infections with H9N2 occurred during 2021 to 2022. In this study, we assess the antigenic and pathogenic impact of 23 hemagglutinin (HA) amino acid mutations. Our study reveals that three specific mutations, labeled R164Q, N166D, and I220T, are responsible for the binding of antibodies with escape mutations. Variants containing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37948179
DOI: 10.1016/j.celrep.2023.113409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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