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Article

Rapid diagnostic tests for malaria diagnosis in Cameroon: impact of histidine rich protein 2/3 deletions and lactate dehydrogenase gene polymorphism.

Diagnostic microbiology and infectious disease - 1 Jan 2024

Nana Rodrigue Roman Dongang, Ngum Ngum Lesly, Makoge Valerie, Amvongo-Adja Nathalie, Hawadak Joseph, Singh Vineeta

Abstract excerpt

Malaria rapid diagnostic tests (mRDT) play a vital role in malaria control in endemic areas. In this study, histidine-rich protein (hrp) and lactate dehydrogenase (ldh) genes were genotyped in Plasmodium falciparum (Pf) and Plasmodium ovale (Po) spp. isolates. Deletions in P. falciparum hrp2/3 (pfhrp2/3) proteins and single nucleotide polymorphisms (SNPs) were analyzed. Twenty-four samples were analyzed for...

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Identifiers

PMID: 37944271
DOI: 10.1016/j.diagmicrobio.2023.116103

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