Article
Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
1 Jan 2023
Abstract excerpt
H istidine-rich protein 2 (HRP2) is the primary target of the Plasmodium falciparum rapid diagnostic tests (RDT) that are a cornerstone of malaria control efforts in the high-burden, low-resource contexts in which malaria mortality is most acute (1). Increasing prevalence of P. falciparum parasites that do not express HRP2 or its paralogue histidine-rich protein 3 (encoded by the pfhrp2 and pfhrp3 genes) are...
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