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Transcriptomic and metabolomic analyses reveal the essential nature of Rab1B in Toxoplasma gondii

8 Nov 2023

Abstract excerpt

BACKGROUND: The protozoan parasite Toxoplasma gondii encodes a dozen Rab proteins, which are parts of the small GTPase superfamily and regulate intracellular membrane trafficking. Our previous study showed that depletion of Rab1B caused severe defects regarding parasite growth and morphological structure, yet early defects of endocytic trafficking and vesicle sorting to the rhoptry in T. gondii are not expected...

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PMID: 37941035
DOI: 10.1186/s13071-023-06030-6

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