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Article

Lipoprotein(a): a genetic marker for cardiovascular disease and target for emerging therapies

27 Aug 2020

Abstract excerpt

Lipoprotein(a) [Lp(a)] is an established cardiovascular risk factor, and growing evidence indicates its causal association with atherosclerotic disease because of the proatherogenic low-density lipoprotein (LDL)-like properties and the prothrombotic plasminogen-like activity of apolipoprotein(a) [apo(a)]. As genetics significantly influences its plasma concentration, Lp(a) is considered an inherited risk factor...

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PMID: 32858625
DOI: 10.2459/jcm.0000000000001077

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