Article
Genetic polymorphisms in vitamin E transport genes as determinants for risk of equine neuroaxonal dystrophy.
Journal of veterinary internal medicine - 1 Jan 2000
Ma Yunzhuo, Peng Sichong, Donnelly Callum G, Ghosh Sharmila, Miller Andrew D, Woolard Kevin, Finno Carrie J
Abstract excerpt
BACKGROUND: Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder associated with vitamin E deficiency. In humans, polymorphisms in genes involved in vitamin E uptake and distribution determines individual vitamin E requirements. HYPOTHESIS/OBJECTIVES: Genetic polymorphisms in genes involved in vitamin E metabolism would be associated with an...
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