Article
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.
Nature - 4 Jul 2013
Orlando Ludovic, Ginolhac Aurélien, Zhang Guojie, Froese Duane, Albrechtsen Anders, Stiller Mathias, Schubert Mikkel, Cappellini Enrico, Petersen Bent, Moltke Ida, Johnson Philip L F, Fumagalli Matteo, Vilstrup Julia T, Raghavan Maanasa, Korneliussen Thorfinn, Malaspinas Anna-Sapfo, Vogt Josef, Szklarczyk Damian, Kelstrup Christian D, Vinther Jakob, Dolocan Andrei, Stenderup Jesper, Velazquez Amhed M V, Cahill James, Rasmussen Morten, Wang Xiaoli, Min Jiumeng, Zazula Grant D, Seguin-Orlando Andaine, Mortensen Cecilie, Magnussen Kim, Thompson John F, Weinstock Jacobo, Gregersen Kristian, Røed Knut H, Eisenmann Véra, Rubin Carl J, Miller Donald C, Antczak Douglas F, Bertelsen Mads F, Brunak Søren, Al-Rasheid Khaled A S, Ryder Oliver, Andersson Leif, Mundy John, Krogh Anders, Gilbert M Thomas P, Kjær Kurt, Sicheritz-Ponten Thomas, Jensen Lars Juhl, Olsen Jesper V, Hofreiter Michael, Nielsen Rasmus, Shapiro Beth, Wang Jun, Willerslev Eske
Abstract excerpt
The rich fossil record of equids has made them a model for evolutionary processes. Here we present a 1.12-times coverage draft genome from a horse bone recovered from permafrost dated to approximately 560-780 thousand years before present (kyr BP). Our data represent the oldest full genome sequence determined so far by almost an order of magnitude. For comparison, we sequenced the genome of a Late Pleistocene...
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