Article
Genome-wide SNP association-based localization of a dwarfism gene in Friesian dwarf horses.
Animal genetics - 1 Dec 2010
Orr N, Back W, Gu J, Leegwater P, Govindarajan P, Conroy J, Ducro B, Van Arendonk J A M, MacHugh D E, Ennis S, Hill E W, Brama P A J
Abstract excerpt
The recent completion of the horse genome and commercial availability of an equine SNP genotyping array has facilitated the mapping of disease genes. We report putative localization of the gene responsible for dwarfism, a trait in Friesian horses that is thought to have a recessive mode of inheritance, to a 2-MB region of chromosome 14 using just 10 affected animals and 10 controls. We successfully genotyped...
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