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Article

Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models.

Genes - 10 Jan 2020

Hales Erin N, Esparza Christina, Peng Sichong, Dahlgren Anna R, Peterson Janel M, Miller Andrew D, Finno Carrie J

Abstract excerpt

Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder of unknown etiology. Clinical signs of neurological deficits develop within the first year of life in vitamin E (vitE) deficient horses. A genome-wide association study (GWAS) was carried out using 670,000 SNP markers in 27 case and 42 control Quarter Horses. Two markers, encompassing a 2.5...

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Identifiers

PMID: 31936863
DOI: 10.3390/genes11010082
PMCID: PMC7016928

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Source receipt: pubmed, retrieved 7 Sept 2026.

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