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Plasma Neuronal Growth Regulator 1 May Link Physical Activity to Reduced Risk of Type 2 Diabetes: A Proteome-Wide Study of ARIC Participants.

Diabetes - 1 Feb 2024

Steffen Brian T, McDonough Daniel J, Pankow James S, Tang Weihong, Rooney Mary R, Demmer Ryan T, Lutsey Pamela L, Guan Weihua, Gabriel Kelley Pettee, Palta Priya, Moser Ethan D, Pereira Mark A

Abstract excerpt

Habitual physical activity (PA) impacts the plasma proteome and reduces the risk of developing type 2 diabetes (T2D). Using a large-scale proteome-wide approach in Atherosclerosis Risk in Communities study participants, we aimed to identify plasma proteins associated with PA and determine which of these may be causally related to lower T2D risk. PA was associated with 92 plasma proteins in discovery (P < 1.01 ×...

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Share to Blood Proteins
Share to Cell Adhesion Molecules, Neuronal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 37935012
DOI: 10.2337/db23-0383
PMCID: PMC10796298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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