Article
Genome-wide association studies of 27 accelerometry-derived physical activity measurements identified novel loci and genetic mechanisms.
Genetic epidemiology - 1 Mar 2022
Qi Guanghao, Dutta Diptavo, Leroux Andrew, Ray Debashree, Muschelli John, Crainiceanu Ciprian, Chatterjee Nilanjan
Abstract excerpt
Physical inactivity (PA) is an important risk factor for a wide range of diseases. Previous genome-wide association studies (GWAS), based on self-reported data or a small number of phenotypes derived from accelerometry, have identified a limited number of genetic loci associated with habitual PA and provided evidence for involvement of central nervous system in mediating genetic effects. In this study, we derived...
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