Article
Diffusion MRI is valuable in brainstem glioma genotyping with quantitative measurements of white matter tracts.
European radiology - 1 May 2024
Xiao Xiong, Yang Ne, Gu Guocan, Wang Xianyu, Jiang Zhuang, Li Tian, Zhang Xinran, Ma Longfei, Zhang Peng, Liao Hongen, Zhang Liwei
Abstract excerpt
OBJECTIVES: To investigate the value of diffusion MRI (dMRI) in H3K27M genotyping of brainstem glioma (BSG). METHODS: A primary cohort of BSG patients with dMRI data (b = 0, 1000 and 2000 s/mm2) and H3K27M mutation information were included. A total of 13 diffusion tensor and kurtosis imaging (DTI; DKI) metrics were calculated, then 17 whole-tumor histogram features and 29 along-tract white matter (WM)...
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