Article
Diffusion MRI-based connectomics features improve the noninvasive prediction of H3K27M mutation in brainstem gliomas.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Sept 2023
Yang Ne, Xiao Xiong, Gu Guocan, Wang Xianyu, Zhang Xinran, Wang Yi, Pan Changcun, Zhang Peng, Ma Longfei, Zhang Liwei, Liao Hongen
Abstract excerpt
PURPOSE: To establish an individualized predictive model to identify patients with brainstem gliomas (BSGs) at high risk of H3K27M mutation, with the inclusion of brain structural connectivity analysis based on diffusion MRI (dMRI). MATERIALS AND METHODS: A primary cohort of 133 patients with BSGs (80 H3K27M-mutant) were retrospectively included. All patients underwent preoperative conventional MRI and dMRI....
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