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Article

Time-dependent diffusion MRI-based microstructural mapping for predicting IDH mutation status in glioma: A multicenter study.

Magnetic resonance imaging - 1 May 2026

Hu Wanjun, Liu Wentao, Li Darui, Niu Liang, Han Yuping, Chang Junwei, Xu Tianyong, Xiong Yuhui, Ouyang Zhiqiang, Liang Qiang, Zhang Jing

Abstract excerpt

OBJECTIVES: To evaluate whether time-dependent diffusion MRI(td-dMRI)-based microstructural histogram parameters can accurately distinguish IDH mutation status in gliomas, with multicenter external validation. METHODS: In this prospective dual-center study, patients with pathologically confirmed glioma underwent preoperative conventional MRI and td-dMRI-based. Microstructural parameters including intracellular...

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PMID: 41422994
DOI: 10.1016/j.mri.2025.110598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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