Article
Impact of non-driver gene mutations on thrombo-haemorrhagic events in ET patients.
British journal of haematology - 1 Jan 2024
Furuya Chiho, Morishita Soji, Hashimoto Yoshinori, Inano Tadaaki, Ochiai Tomonori, Shirane Shuichi, Edahiro Yoko, Araki Marito, Ando Miki, Komatsu Norio
Abstract excerpt
Risk-adapted therapy is recommended to prevent major clinical complications, such as thrombo-haemorrhagic events, in patients with essential thrombocythaemia (ET). In this study, we analysed the association between non-driver gene mutations and thrombo-haemorrhagic events in 579 patients with ET. ASXL1 and TP53 mutations were frequently identified in patients with ET complicated by thrombosis (22.7% and 23.1%,...
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