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Article

MPL gene mutation is a possible risk factor for thrombosis in patients with essential thrombocythemia in Japan.

Hematology (Amsterdam, Netherlands) - 1 Dec 2023

Furuya Chiho, Hashimoto Yoshinori, Morishita Soji, Inano Tadaaki, Ochiai Tomonori, Shirane Shuichi, Edahiro Yoko, Araki Marito, Ando Miki, Komatsu Norio

Abstract excerpt

OBJECTIVES: Since MPL mutation is a rare driver gene mutation found in a small number of essential thrombocythemia (ET) patients, the clinical characteristics of patients with MPL mutations and their association with thrombotic events have not yet been elucidated in Japan. METHODS: We enrolled 579 Japanese ET patients based on the diagnostic criteria of the WHO classification 2017 and compared clinical...

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PMID: 37378567
DOI: 10.1080/16078454.2023.2229131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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