Risk factors for thrombosis and bleeding and their influence on therapeutic decisions in patients with essential thrombocythemia.

Abstract excerpt

The clinical course of essential thrombocythemia (ET) is variable, ranging from microvascular circulation disturbances to severe thromboembolic or hemorrhagic complications in patients who do not have any symptoms for many years. The identification of patients at risk for major thrombosis who need platelet-lowering therapy is important. During the last two decades, several risk factors for the development of...

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