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Article

Association of Somatic TET2 Mutations With Giant Cell Arteritis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Mar 2024

Robinette Michelle L, Weeks Lachelle D, Kramer Ryan J, Agrawal Mridul, Gibson Christopher J, Yu Zhi, Sekar Aswin, Mehta Arnav, Niroula Abhishek, Brown Jared T, McDermott Gregory C, Reshef Edith R, Lu Jonathan E, Liou Victor D, Chiou Carolina A, Natarajan Pradeep, Freitag Suzanne K, Rao Deepak A, Ebert Benjamin L

Abstract excerpt

OBJECTIVE: Giant cell arteritis (GCA) is an age-related vasculitis. Prior studies have identified an association between GCA and hematologic malignancies (HMs). How the presence of somatic mutations that drive the development of HMs, or clonal hematopoiesis (CH), may influence clinical outcomes in GCA is not well understood. METHODS: To examine an association between CH and GCA, we analyzed sequenced exomes of...

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Identifiers

PMID: 37909388
DOI: 10.1002/art.42738
PMCID: PMC10922498

Genes

GCA
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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