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Article

Norovirus evolves as one or more distinct clonal populations in immunocompromised hosts.

mBio - 19 Dec 2023

Chaimongkol Natthawan, Dábilla Nathânia, Tohma Kentaro, Matsushima Yuki, Yardley Allison Behrle, Levenson Eric A, Johnson Jordan A, Ahorrio Courtney, Oler Andrew J, Kim Daniel Y, Souza Menira, Sosnovtsev Stanislav V, Parra Gabriel I, Green Kim Y

Abstract excerpt

IMPORTANCE: Noroviruses are an important cause of chronic diarrhea in patients with compromised immune systems. Presently, there are no effective therapies to clear the virus, which can persist for years in the intestinal tract. The goal of our study was to develop a better understanding of the norovirus strains that are associated with these long-term infections. With the remarkable diversity of norovirus...

Topics

Norovirus
Humans
Immunocompromised Host
Caliciviridae Infections
High-Throughput Nucleotide Sequencing
Genome, Viral
Phylogeny
Evolution, Molecular
Genetic Variation
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gastroenteritis

Virus Shedding

Source

Open in PubMed Open full text

Identifiers

PMID: 37905910
DOI: 10.1128/mbio.02177-23
PMCID: PMC10746188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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