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Article

What is the reservoir of emergent human norovirus strains?

Journal of virology - 1 Jun 2015

Karst Stephanie M, Baric Ralph S

Abstract excerpt

Since 1996, there have been at least six human norovirus pandemics. All of the pandemic strains are genetically related, segregating in the genogroup II, genotype 4 (GII.4) cluster within the Norovirus genus. Evidence indicates that these strains are closely related but antigenically distinct, supporting immune-driven viral evolution. Thus, norovirus vaccines will likely require periodic reformulation to protect...

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Identifiers

PMID: 25787285
DOI: 10.1128/JVI.03063-14
PMCID: PMC4442419

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