Norovirus genetic diversity and evolution: implications for antiviral therapy.

doi:10.1016/j.coviro.2016.09.009

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Article

Norovirus genetic diversity and evolution: implications for antiviral therapy.

Current opinion in virology - 1 Oct 2016

Rocha-Pereira Joana, Van Dycke Jana, Neyts Johan

Abstract excerpt

Human noroviruses are the leading cause of foodborne illness causing both acute and chronic gastroenteritis. In recent years, a number of vaccine candidates entered (pre-) clinical development and the first efforts to develop antiviral therapy have been made. We here discuss aspects of norovirus genetic evolution, persistence in immunocompromised patients as well as the risk and potential consequences of...

Topics

Antiviral Agents
Caliciviridae Infections
Drug Resistance, Viral
Foodborne Diseases
Gastroenteritis
Genetic Variation
Humans
Norovirus

Source

Open in PubMed

Identifiers

PMID: 27736665
DOI: 10.1016/j.coviro.2016.09.009

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