Article
[DDB2-associated incidence of squamous cell carcinoma in Haflingers: risk minimization by genotyping].
Schweizer Archiv fur Tierheilkunde - 1 Nov 2023
Schäfer J, May A, Wittenberg J, Hahn K, Graubner C, Gerber V, Drögemüller C, Unger L
Abstract excerpt
INTRODUCTION: SCC (squamous cell carinomas) are among the most common eye neoplasms in horses. In recent studies Haflinger horses with a homozygous genotype for a missense variant in the DDB2 gene (damage specific DNA binding protein 2) had a significant increased risk of developing ocular SCC. The aims of this study were to determine the frequency of the SCC-associated risk allele in the DDB2 gene in Swiss and...
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