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Article

Suppression of E6 Oncogene Induces Apoptosis in CaSki Cervical Cancer Cells

1 Oct 2023

Abstract excerpt

OBJECTIVE: The most important casuse of cervical cancer incidence and high mortality rate is infection to the human papillomavirus (HPV). The aim of the present study was to investigate the effect of silencing HPV E6 oncogene on cervical cancer cells using specific siRNAs. MATERIALS AND METHODS: CaSki cervical cancer cells, carrying E6 gene, were cultured and then transfected with E6 targeting siRNAs. The cell...

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PMID: 37898842
DOI: 10.31557/apjcp.2023.24.10.3389

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