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Article

Molecular dynamics simulation of RAC1 protein and its de novo variants related to developmental disorders.

Journal of biomolecular structure & dynamics - 1 Jan 2024

Rani Nigam, Boora Nisha, Rani Reena, Kumar Vinay, Ahalawat Navjeet

Abstract excerpt

Neurodevelopmental disorders (NDDs) are conceptualized as childhood disability, but it has increasingly been recognized as lifelong neurological conditions that could notably impact adult functioning and quality of life. About 1%-3% of the general population suffers from NDDs including ADHD, ASD, IDD, communication disorders, motor disorders, etc. Studies suggest that Rho GTPases are key in neuronal development,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37897175
DOI: 10.1080/07391102.2023.2275188

Genes

RAC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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