Article
Systematic replication of smoking disease associations using survey responses and EHR data in the All of Us Research Program.
Journal of the American Medical Informatics Association : JAMIA - 22 Dec 2023
Schlueter David J, Sulieman Lina, Mo Huan, Keaton Jacob M, Ferrara Tracey M, Williams Ariel, Qian Jun, Stubblefield Onajia, Zeng Chenjie, Tran Tam C, Bastarache Lisa, Dai Jian, Babbar Anav, Ramirez Andrea, Goleva Slavina B, Denny Joshua C
Abstract excerpt
OBJECTIVE: The All of Us Research Program (All of Us) aims to recruit over a million participants to further precision medicine. Essential to the verification of biobanks is a replication of known associations to establish validity. Here, we evaluated how well All of Us data replicated known cigarette smoking associations. MATERIALS AND METHODS: We defined smoking exposure as follows: (1) an EHR Smoking exposure...
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