Article
A large cohort of deletional high hemoglobin F determinants in Thailand: A molecular revisited and identification of a novel mutation.
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2023
Singha Kritsada, Tepakhan Wanicha, Yamsri Supawadee, Chaibunruang Attawut, Srivorakun Hataichanok, Pansuwan Anupong, Fucharoen Goonnapa, Fucharoen Supan
Abstract excerpt
BACKGROUND AND AIMS: High hemoglobin F determinants can be classified into hereditary persistence of fetal hemoglobin (HPFH) and δβ-thalassemia with different phenotype. We report the molecular basis and hematological features in a large cohort of deletional high Hb F determinants in Thailand. MATERIALS AND METHODS: Subjects (n = 28,177) encountered during 2015-2022 were reviewed, and those with phenotypically...
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