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Article

Molecular basis and hematologic characterization of deltabeta-thalassemia and hereditary persistence of fetal hemoglobin in Thailand.

Haematologica - 1 Jul 2004

Panyasai Sitthichai, Fucharoen Supan, Surapot Satja, Fucharoen Goonnapa, Sanchaisuriya Kanokwan

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hereditary persistence of fetal hemoglobin (HPFH) and deltabeta-thalassemia are heterogeneous disorders characterized by increased levels of Hb F in adult life. The distinction between these two conditions is not always possible from routine hematologic analyses. This study investigated the hematologic and molecular characteristics of high HbF determinants in Thailand, and describes a...

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PMID: 15257928

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