Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common hemoglobin variants affecting the diagnosis of β-thalassemia: A large cohort data at a single center.

PloS one - 1 Jan 2026

Singha Kritsada, Srivorakun Hataichanok, Yamsri Supawadee, Chaibunruang Attawut, Pansuwan Anupong, Changtrakul Yossombat, Sanchisuriya Kanokwan, Fucharoen Goonnapa, Fucharoen Supan

Abstract excerpt

BACKGROUND: Many globin chain variants were interpreted as β-thalassemia or hereditary persistence of fetal hemoglobin (HPFH) at routine investigation. We described this in a large cohort of Thai subjects. METHODS: Hematological data of 43,414 subjects encountered at our thalassemia diagnostic center from January 2013 to July 2025 were reviewed. A total of 372 subjects with hemoglobin (Hb) variants were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Globins
Share to beta-Thalassemia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to Fetal Hemoglobin

Share to Hemoglobin A2

Share to Hemoglobins

Share to Hemoglobins, Abnormal

Share to Thailand

Source

Open in PubMed Open full text

Identifiers

PMID: 41996320
DOI: 10.1371/journal.pone.0346729
PMCID: PMC13089717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common hemoglobin variants affecting the diagnosis of β-thalassemia: A large cohort data at a single center.PMID 41996320Read ↗

Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β-Thalassemia Screening.Semantic proximity Read ↗

A large cohort of deletional high hemoglobin F determinants in Thailand: A molecular revisited and identification of a novel mutation.Semantic proximity Read ↗

A large cohort of hemoglobin variants in Thailand: molecular epidemiological study and diagnostic consideration.Semantic proximity Read ↗

Complex interaction of δ-globin variant HbA2-Famagusta combined with β-globin variant Hb Monroe in cis with the HBB:c.-92C>G mutation: hematological characteristics and molecular diagnostic insights.Semantic proximity Read ↗

A large cohort of Hb H disease in northeast Thailand: A molecular revisited, diverse genetic interactions and identification of a novel mutation.Semantic proximity Read ↗

Molecular spectrum of Hb H disease and characterization of rare deletional α-thalassemia found in ThailandSemantic proximity Read ↗

Analysis of genotypic distribution and rare variants of patients with α/β-thalassemia screened in one hospital in Beijing, China.Semantic proximity Read ↗

Known and new hemoglobin A2 variants in Thailand and implication for β-thalassemia screening.Semantic proximity Read ↗

Compound Heterozygous Hemoglobin Minneapolis-Laos and Codon 41/42 (-TTCT) in a Thai Female Adult: A Case Report and Literature Review.Semantic proximity Read ↗

Molecular epidemiology and hematological profiles of hemoglobin variants in southern Thailand.Semantic proximity Read ↗

Problems in determining thalassemia carrier status in a program for prevention and control of severe thalassemia syndromes: a lesson from Thailand.Semantic proximity Read ↗

Prospective screening for δ-hemoglobinopathies associated with decreased hemoglobin A2 levels or hemoglobin A2 variants: A single center experience.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.