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Article

NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

25 Oct 2023

Abstract excerpt

Glioblastoma is a severe brain tumor characterized by an extremely poor survival rate of patients. Glioblastoma cancer cells escape to standard therapeutic protocols consisting of a combination of ionizing radiation and temozolomide alkylating drugs that trigger DNA damage by rewiring of signaling pathways. In recent years, the up-regulation of factors that counteract ferroptosis has been highlighted as a major...

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PMID: 37879937
DOI: 10.26508/lsa.202302205

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