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A role for ceruloplasmin in the control of human glioblastoma cell responses to radiation

2 Aug 2022

Abstract excerpt

Abstract Background Glioblastoma (GB) is the most common and most aggressive malignant brain tumor. In understanding its resistance to conventional treatments, iron metabolism and related pathways may represent a novel avenue. As for many cancer cells, GB cell growth is dependent on iron, which is tightly involved in red-ox reactions related to radiotherapy effectiveness. From new observations indicating an...

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PMID: 35918659
DOI: 10.1186/s12885-022-09808-6

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