Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NUPR1 Promotes Radioresistance in Colorectal Cancer Cells by Inhibiting Ferroptosis

1 Apr 2025

Abstract excerpt

Radioresistance is a major clinical challenge and the underlying mechanism has not been thoroughly elucidated. In this study, a radioresistant (RR) cell line is established to explore the transcriptomic signatures of radioresistance in colorectal cancer (CRC). KEGG enriched pathway analysis demonstrated that ferroptosis is inactivated in RR cells. Further detection confirmed that radiotherapy can promote...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40176685
DOI: 10.1111/jcmm.70519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NUPR1 Promotes Radioresistance in Colorectal Cancer Cells by Inhibiting FerroptosisPMID 40176685Read ↗

Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance‐mediated oxaliplatin chemoresistance in colorectal cancerSemantic proximity Read ↗

LncRNA ALMS1 ‐ IT1 modulates ferroptosis and immune evasion in colorectal cancer through activating STAT3Semantic proximity Read ↗

LncRNA FTX promotes colorectal cancer radioresistance through disturbing redox balance and inhibiting ferroptosis via miR-625-5p/SCL7A11 axisSemantic proximity Read ↗

Insights on Ferroptosis and Colorectal Cancer: Progress and UpdatesSemantic proximity Read ↗

Ferroptosis: Reviewing CRC with the Third EyeSemantic proximity Read ↗

The correlation of ferroptosis and DNA repair in individuals with colorectal cancerSemantic proximity Read ↗

A Novel Ferroptosis-related Lncrna Prognostic Signature for Colorectal Cancer by Bioinformatics AnalysisSemantic proximity Read ↗

MAPK Signaling‐Mediated RFNG Phosphorylation and Nuclear Translocation Restrain Oxaliplatin‐Induced Apoptosis and FerroptosisSemantic proximity Read ↗

Patients‐Derived Organoids Sequencing‐based FOXP4 Facilitates Radioresistance by Transcriptionally Modifying GPX4 to Regulate ferroptosis in Colorectal CancerSemantic proximity Read ↗

WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancerSemantic proximity Read ↗

GINS4 suppresses ferroptosis by antagonizing p53 acetylation with SnailSemantic proximity Read ↗

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.