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Article

Notch receptor/ligand diversity: contribution to colorectal cancer stem cell heterogeneity

4 Oct 2023

Abstract excerpt

Cancer cell heterogeneity is a key contributor to therapeutic failure and post-treatment recurrence. Targeting cell subpopulations responsible for chemoresistance and recurrence seems to be an attractive approach to improve treatment outcome in cancer patients. However, this remains challenging due to the complexity and incomplete characterization of tumor cell subpopulations. The heterogeneity of cells...

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Identifiers

PMID: 37860822
DOI: 10.3389/fcell.2023.1231416

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