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Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer

2023-02-06

Abstract excerpt

<h4>ABSTRACT</h4> One reason for lack of efficacy in cancer therapeutics is tumor heterogeneity. We hypothesize that tumor heterogeneity arises due to emergence of multiple cancer stem cell (CSC) subpopulations because miRNAs regulate expression of stem cell genes in CSCs. Our goal was to determine if: i ) multiple CSC subpopulations exist in a human CRC cell population, and ii ) miRNAs are differentially expre...

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Literature Corpus work
1f30ce02-c240-549e-9467-8c05e7748f02
DOI
10.1101/2023.02.06.527341
Open publication

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Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal CancerDOI 10.1101/2023.02.06.527341
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