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Colorectal Cancer Stem Cells

9 Jan 2012

Abstract excerpt

Colorectal cancer (CRC) is one of the most commonly diagnosed and lethal cancers worldwide. It is a multistep process that requires the accumulation of genetic/epigenetic aberrations. There are several issues concerning colorectal carcinogenesis that remain unanswered, such as the cell of origin and the type of cells that propagate the tumor after its initiation. There are two models of carcinogenesis: the...

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PMID: 22232074
DOI: 10.1002/stem.1031

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