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Article

Effects of modulator therapies on endocrine complications in adults with cystic fibrosis: a narrative review.

The Medical journal of Australia - 20 Nov 2023

Kumar Shanal, Soldatos Georgia, Teede Helena J, Pallin Michael

Abstract excerpt

Cystic fibrosis is a monogenic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, which transports chloride ions in secretory organs. Modulator therapies are small molecules that correct CFTR dysfunction and can lead to a wide range of benefits for both pulmonary and extrapulmonary complications of cystic fibrosis. With advancements in airway, antimicrobial and...

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Identifiers

PMID: 37839059
DOI: 10.5694/mja2.52119

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