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Article

An Update on CFTR Modulators as New Therapies for Cystic Fibrosis.

Paediatric drugs - 1 Jul 2022

King John A, Nichols Anna-Louise, Bentley Sian, Carr Siobhan B, Davies Jane C

Abstract excerpt

Over the past decade there have been significant developments in the field of Cystic Fibrosis Transmembrane Regulator modulator drugs. Following treatment in patients with cystic fibrosis with common gating mutations using the potentiator drug ivacaftor, successive development of corrector drugs used in combination has led to highly effective modulator therapy being available to more than 85% of the cystic...

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PMID: 35570261
DOI: 10.1007/s40272-022-00509-y

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