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Article

The endolysosomal pathway and ALS/FTD.

Trends in neurosciences - 1 Dec 2023

Todd Tiffany W, Shao Wei, Zhang Yong-Jie, Petrucelli Leonard

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are considered to be part of a disease spectrum that is associated with causative mutations and risk variants in a wide range of genes. Mounting evidence indicates that several of these genes are linked to the endolysosomal system, highlighting the importance of this pathway in ALS/FTD. Although many studies have focused on how disruption of...

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Identifiers

PMID: 37827960
DOI: 10.1016/j.tins.2023.09.004
PMCID: PMC10841821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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