Article
Enhanced recovery in patients with gestational diabetes mellitus and MTHFR 677 TT genotype after taking high-dose folic acid supplements during mid-late pregnancy: an open-label interventional study.
Frontiers in endocrinology - 1 Jan 2023
Ying Jun, Zhang Jie, Li Piyu, Liu Lu, Li Yan, Lau Winnie W Y, Chu Qiao, Wu Benqing, Wang Xiaonan, Zhang Hui
Abstract excerpt
Objective: To explore the relationship between folic acid supplementation and the recovery rate of gestational diabetes mellitus (GDM) in women with methylenetetrahydrofolate (MTHFR) 677 TT genotypes in mid-late pregnancy. Methods: 9, 096 pregnant women were recruited with their MTHFR gene genotyped. 5,111 women underwent a 75-g oral glucose tolerance test (OGTT) and 2,097 were confirmed with GDM. The association...
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