Article
Increasing prevalence of gestational diabetes mellitus when carrying the T variant allele of the MTHFR gene C677T polymorphism: a systematic review and meta-analysis.
Archives of gynecology and obstetrics - 1 May 2022
Chen Yanjie, Lu Minyan, Nie Jinyi, Liu Jianjun, Liu Yu, Meng Ye, Sun Xiaohan, Ji Cheng, Zhang Jie, Yang Xiaoqin
Abstract excerpt
PURPOSE: Previous epidemiological data linking the C677T and A1298C MTHFR polymorphisms to gestational diabetes risk have been mixed and controversial. Therefore, we conducted this meta-analysis to derive a more precise estimation of the relationship between MTHFR polymorphisms and this pregnancy disorder. METHODS: A systematic literature search for original epidemiological studies was performed in the CNKI,...
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