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Associations Between Gestational Diabetes Mellitus Risk and Folate Status in Early Pregnancy and MTHFR C677T Polymorphisms in Chinese Women

1 May 2020

Abstract excerpt

Purpose: Red blood cell (RBC) folate indicates long-term folate intake, and methylenetetrahydrofolate reductase ( MTHFR ) gene is the main gene affecting folate status. Increasing evidence suggests an association between gestational diabetes mellitus (GDM) and increased folate levels. Whether RBC folate concentrations in the first trimester of pregnancy or polymorphisms of MTHFR C677T (rs1801133) affect GDM risk...

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PMID: 32440179
DOI: 10.2147/dmso.s250279

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