Article
Could NCOA5 a novel candidate gene for multiple sclerosis susceptibility?
Molecular biology reports - 1 Nov 2023
Rustemoglu Husniye, Arslan Erdem, Atasever Sema, Cevik Betul, Taspinar Filiz, Turhan Ahmet Bülent, Rustemoglu Aydin
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is an inflammatory immune-mediated demyelinating disease that causes a challenging and disabling condition. Environmental and genetic factors play a role in appearing the state of the disease. Recent studies have shown that nuclear cofactor genes may play a role in the pathogenesis of MS. NCOA5 is a nuclear receptor coactivator independent of AF2 that modulates ERa-mediated...
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