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Proteomics of CKD progression in the chronic renal insufficiency cohort

10 Oct 2023

Abstract excerpt

Progression of chronic kidney disease (CKD) portends myriad complications, including kidney failure. In this study, we analyze associations of 4638 plasma proteins among 3235 participants of the Chronic Renal Insufficiency Cohort Study with the primary outcome of 50% decline in estimated glomerular filtration rate or kidney failure over 10 years. We validate key findings in the Atherosclerosis Risk in the...

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PMID: 37816758
DOI: 10.1038/s41467-023-41642-7

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